Question by : What are the advantages and disadvantages of taking Carim 100 mg?
I am intrigued specifically what are the benefits and drawbacks of having Modafinil 200 mg? Many thanks much.

Best answer:

Answer by Colin
Carim is just another name for modafinil… the only difference in yours is 100mg is half the dose of the 200mg tablets.

In the United States, modafinil is approved by the U.S. Food and Drug Administration only for the treatment of narcolepsy, obstructive sleep apnea/hypopnea and shift work sleep disorder. In some countries, it is also approved for idiopathic hypersomnia (all forms of excessive daytime sleepiness where causes can’t be established). The usual prescribed dosage for these disorders is 200 mg once a day (less commonly, 100 to 400 mg/day in one or two doses).

For conditions other than shift work sleep disorder, modafinil is normally taken in one dose in the morning or in two doses in the morning and at midday. It is generally not recommended to take modafinil after noon: modafinil is a relatively long-acting drug with a half-life of 15 hours, and taking it during the later part of the day carries a risk of sleep disturbances

Despite extensive research into the interaction of modafinil with a large number of neurotransmitter systems, a precise mechanism or set of mechanisms of action remains unclear. It seems that modafinil, like other stimulants, increases the release of monoamines, specifically the catecholamines norepinephrine and dopamine, from the synaptic terminals. However, modafinil also elevates hypothalamic histamine levels, leading some researchers to consider Modafinil a “wakefulness promoting agent” rather than a classic amphetamine-like stimulant. Despite modafinil’s histaminergic action, it still partially shares the actions of amphetamine-class stimulants due to its effects on norepinephrine and dopamine.

A National Institute on Alcohol Abuse and Alcoholism (NIAAA) study highlighted “the need for heightened awareness for potential abuse of and dependence on modafinil in vulnerable populations” due to the drug’s effect on dopamine in the brain’s reward center. However, the synergistic actions of modafinil on both catecholaminergic and histaminergic pathways lowers abuse potential as compared to traditional stimulant drugs while maintaining the effectiveness of the drug as a wakefulness promoting agent. Studies have suggested that modafinil “has limited potential for large-scale abuse” and “does not possess an addictive potential in naive individuals.”

Modafinil was shown to be an effective treatment for attention deficit hyperactivity disorder (ADHD),however in 2006 it was found by the FDA to be unfit for use by children for that purpose. It was rejected primarily due to one suspected case of Stevens-Johnson syndrome. Cephalon’s own label for Provigil now discourages its use by children for any purpose. Other potentially effective, but unapproved targets include the treatment of depression, bipolar depression,opiate & cocaine dependence,Parkinson’s disease, schizophrenia, and disease-related fatigue, as well as fatigue that is the side effect of another medication.

In most countries, here is a paper sheet with this sort of information with the tablets. If not, you really should discuss what you need to know with the pharmacist. Although pharmacists are sometimes called chemists, they are rather different and have specific traning in the areas.

Know better? Leave your own answer in the comments!

Question by Maryy: What percent of rehabilitated people actually are cured?
ok so this is for a project….
does anyone know what percent of rehabilitated people get out and dont do the same mistake agian??? (i.e.- they would use drugs daily, went to rehab, then when they got out they quit completly)
i searched yahoo, google, and ask jeeves. i did all of my project and this is just a small part of it wich isnt really gonna be graded so keep your useless coments to yourself

Best answer:

Answer by raysny
Rehabs often claim amazing results, but the reality is less than spectacular.

According to Wikipedia:
http://en.wikipedia.org/wiki/Alcohol_addiction
“The effectiveness of alcoholism treatments varies widely. When considering the effectiveness of treatment options, one must consider the success rate based on those who enter a program, not just those who complete it. Since completion of a program is the qualification for success, success among those who complete a program is generally near 100%. It is also important to consider not just the rate of those reaching treatment goals but the rate of those relapsing. Results should also be compared to the roughly 5% rate at which people will quit on their own. A year after completing a rehab program, about a third of alcoholics are sober, an additional 40 percent are substantially improved but still drink heavily on occasion, and a quarter have completely relapsed.”

That estimate is based on information from Dr. Mark Willenbring of the National Institute on Alcohol Abuse and Alcoholism, and in my opinion, optomistic.

” About 80 percent of addiction patients will relapse, studies suggest, and long-term success rates for treatment are estimated at 10-30 percent.
“The therapeutic community claims a 30 percent success rate, but they only count people who complete the program,” noted Joseph A. Califano Jr., of the National Center on Addiction and Substance Abuse at Columbia University. “Seventy to eighty percent drop out in three to six months.” ”
http://www.addictioninfo.org/articles/1633/1/Little-Evidence-that-Costly-Treatment-Programs-Work/Page1.html

90-95% of rehabs in the US are 12step-based. The rest are Scientology or religion-based.

The 12step treatment method has been shown to have about a 5% success rate, the same as no treatment at all:

Although the success rate is the same, AA harms more people than no treatment:
1) Dr. Brandsma found that A.A. increased the rate of binge drinking, and
2) Dr. Ditman found that A.A. increased the rate of rearrests for public drunkenness, and
3) Dr. Walsh found that “free A.A.” made later hospitalization more expensive, and
4) Doctors Orford and Edwards found that having a doctor talk to the patient for just one hour was just as effective as a whole year of A.A.-based treatment.
5) Dr. George E. Vaillant, the A.A. Trustee, found that A.A. treatment was completely ineffective, and raised the death rate in alcoholics. No other way of treating alcoholics produced such a high death rate as did Alcoholics Anonymous.
http://www.orange-papers.org/orange-letters85.html

1) http://www.orange-papers.org/orange-effectiveness.html#Brandsma
2) http://www.orange-papers.org/orange-effectiveness.html#Ditman
3) http://www.orange-papers.org/orange-effectiveness.html#Walsh
4) http://www.orange-papers.org/orange-effectiveness.html#Orford
5) http://www.orange-papers.org/orange-effectiveness.html#Vaillant

What do you think? Answer below!

The institutes on alcohol abuse are great initiative that promotes & supports against alcoholism and strives to spread the health benefits for all. Alcoholism abuse is growing at a great pace. The life style today is so stressful that people tend to get to the easy resort of consuming alcohol and drugs. The time is such that not only the colleges, but the school kids are not untouched by the alcohol and drugs. Looking at the need, there are various centers offering help and treatments. Such institutes have become quite dense. The sole reason of such centers is to simply control and cure alcoholism. Having said that it really doesn’t matter how many of such centers are inaugurated, till the time people themselves does not realize that alcohol and drug could not only deteriorate their health, but would also ruin their family life. There are many initiatives taken at national level as well like by the national institute on alcohol abuse and alcoholism to control and provide treatments free or at subsidized cost, the only endeavor being saving the society from the clutches of alcoholism abuse.

As a responsible individual, one must contribute by shouldering the responsibility of checking for alcohol addicts in once own vicinity. Small contributions such as directing people to alcohol treatments, making them understand the real endeavor of such initiates and moreover, motivating the non-alcoholics to support individuals who are addicted rather than think of them as a taboo. This would really make a difference. One national institute on alcoholism and alcoholism despite doing its best can’t make a change in the society; it is us who would take small steps to eliminate alcohol abuse with a broader vision of help & support to such addicts. Understanding the people, who have gotten into the vicious circle of alcoholism, by extending love and care instead of treating them as untouchables, could be certain small steps that could help the victims of alcoholism abuse go a long way – by the end of which, they would gain the same respect and social status that they had before being addicted.

Alcohol treatments would help the addicts to get rid of the addiction but it is our responsibility to give these addicts an environment of support & motivation which would help then to rebuild their identity. The science of health and treatment of alcoholism abuse could be prevented by –

Spreading awareness around the biological behaviors & functioning related to alcohol abuse.
Improvising the quality of diagnosis, treatment and prevention of alcoholism.
Promoting better health care.

http://treatmentcentersdirectory.com/drug-treatment/ Oramorph Addiction & Oramorph Abuse – We can help you discover the best treatment options for you – call…
Video Rating: 0 / 5

Question by Maryy: What percent of rehabilitated people actually are cured?
ok so this is for a project….
does anyone know what percent of rehabilitated people get out and dont do the same mistake agian??? (i.e.- they would use drugs daily, went to rehab, then when they got out they quit completly)
i searched yahoo, google, and ask jeeves. i did all of my project and this is just a small part of it wich isnt really gonna be graded so keep your useless coments to yourself

Best answer:

Answer by raysny
Rehabs often claim amazing results, but the reality is less than spectacular.

According to Wikipedia:
http://en.wikipedia.org/wiki/Alcohol_addiction
“The effectiveness of alcoholism treatments varies widely. When considering the effectiveness of treatment options, one must consider the success rate based on those who enter a program, not just those who complete it. Since completion of a program is the qualification for success, success among those who complete a program is generally near 100%. It is also important to consider not just the rate of those reaching treatment goals but the rate of those relapsing. Results should also be compared to the roughly 5% rate at which people will quit on their own. A year after completing a rehab program, about a third of alcoholics are sober, an additional 40 percent are substantially improved but still drink heavily on occasion, and a quarter have completely relapsed.”

That estimate is based on information from Dr. Mark Willenbring of the National Institute on Alcohol Abuse and Alcoholism, and in my opinion, optomistic.

” About 80 percent of addiction patients will relapse, studies suggest, and long-term success rates for treatment are estimated at 10-30 percent.
“The therapeutic community claims a 30 percent success rate, but they only count people who complete the program,” noted Joseph A. Califano Jr., of the National Center on Addiction and Substance Abuse at Columbia University. “Seventy to eighty percent drop out in three to six months.” ”
http://www.addictioninfo.org/articles/1633/1/Little-Evidence-that-Costly-Treatment-Programs-Work/Page1.html

90-95% of rehabs in the US are 12step-based. The rest are Scientology or religion-based.

The 12step treatment method has been shown to have about a 5% success rate, the same as no treatment at all:

Although the success rate is the same, AA harms more people than no treatment:
1) Dr. Brandsma found that A.A. increased the rate of binge drinking, and
2) Dr. Ditman found that A.A. increased the rate of rearrests for public drunkenness, and
3) Dr. Walsh found that “free A.A.” made later hospitalization more expensive, and
4) Doctors Orford and Edwards found that having a doctor talk to the patient for just one hour was just as effective as a whole year of A.A.-based treatment.
5) Dr. George E. Vaillant, the A.A. Trustee, found that A.A. treatment was completely ineffective, and raised the death rate in alcoholics. No other way of treating alcoholics produced such a high death rate as did Alcoholics Anonymous.
http://www.orange-papers.org/orange-letters85.html

1) http://www.orange-papers.org/orange-effectiveness.html#Brandsma
2) http://www.orange-papers.org/orange-effectiveness.html#Ditman
3) http://www.orange-papers.org/orange-effectiveness.html#Walsh
4) http://www.orange-papers.org/orange-effectiveness.html#Orford
5) http://www.orange-papers.org/orange-effectiveness.html#Vaillant

Know better? Leave your own answer in the comments!

The institutes on alcohol abuse are great initiative that promotes & supports against alcoholism and strives to spread the health benefits for all. Alcoholism abuse is growing at a great pace. The life style today is so stressful that people tend to get to the easy resort of consuming alcohol and drugs. The time is such that not only the colleges, but the school kids are not untouched by the alcohol and drugs. Looking at the need, there are various centers offering help and treatments. Such institutes have become quite dense. The sole reason of such centers is to simply control and cure alcoholism. Having said that it really doesn’t matter how many of such centers are inaugurated, till the time people themselves does not realize that alcohol and drug could not only deteriorate their health, but would also ruin their family life. There are many initiatives taken at national level as well like by the national institute on alcohol abuse and alcoholism to control and provide treatments free or at subsidized cost, the only endeavor being saving the society from the clutches of alcoholism abuse.

As a responsible individual, one must contribute by shouldering the responsibility of checking for alcohol addicts in once own vicinity. Small contributions such as directing people to alcohol treatments, making them understand the real endeavor of such initiates and moreover, motivating the non-alcoholics to support individuals who are addicted rather than think of them as a taboo. This would really make a difference. One national institute on alcoholism and alcoholism despite doing its best can’t make a change in the society; it is us who would take small steps to eliminate alcohol abuse with a broader vision of help & support to such addicts. Understanding the people, who have gotten into the vicious circle of alcoholism, by extending love and care instead of treating them as untouchables, could be certain small steps that could help the victims of alcoholism abuse go a long way – by the end of which, they would gain the same respect and social status that they had before being addicted.

Alcohol treatments would help the addicts to get rid of the addiction but it is our responsibility to give these addicts an environment of support & motivation which would help then to rebuild their identity. The science of health and treatment of alcoholism abuse could be prevented by –

Spreading awareness around the biological behaviors & functioning related to alcohol abuse.
Improvising the quality of diagnosis, treatment and prevention of alcoholism.
Promoting better health care.

Question by Maryy: What percent of rehabilitated people actually are cured?
ok so this is for a project….
does anyone know what percent of rehabilitated people get out and dont do the same mistake agian??? (i.e.- they would use drugs daily, went to rehab, then when they got out they quit completly)
i searched yahoo, google, and ask jeeves. i did all of my project and this is just a small part of it wich isnt really gonna be graded so keep your useless coments to yourself

Best answer:

Answer by raysny
Rehabs often claim amazing results, but the reality is less than spectacular.

According to Wikipedia:
http://en.wikipedia.org/wiki/Alcohol_addiction
“The effectiveness of alcoholism treatments varies widely. When considering the effectiveness of treatment options, one must consider the success rate based on those who enter a program, not just those who complete it. Since completion of a program is the qualification for success, success among those who complete a program is generally near 100%. It is also important to consider not just the rate of those reaching treatment goals but the rate of those relapsing. Results should also be compared to the roughly 5% rate at which people will quit on their own. A year after completing a rehab program, about a third of alcoholics are sober, an additional 40 percent are substantially improved but still drink heavily on occasion, and a quarter have completely relapsed.”

That estimate is based on information from Dr. Mark Willenbring of the National Institute on Alcohol Abuse and Alcoholism, and in my opinion, optomistic.

” About 80 percent of addiction patients will relapse, studies suggest, and long-term success rates for treatment are estimated at 10-30 percent.
“The therapeutic community claims a 30 percent success rate, but they only count people who complete the program,” noted Joseph A. Califano Jr., of the National Center on Addiction and Substance Abuse at Columbia University. “Seventy to eighty percent drop out in three to six months.” ”
http://www.addictioninfo.org/articles/1633/1/Little-Evidence-that-Costly-Treatment-Programs-Work/Page1.html

90-95% of rehabs in the US are 12step-based. The rest are Scientology or religion-based.

The 12step treatment method has been shown to have about a 5% success rate, the same as no treatment at all:

Although the success rate is the same, AA harms more people than no treatment:
1) Dr. Brandsma found that A.A. increased the rate of binge drinking, and
2) Dr. Ditman found that A.A. increased the rate of rearrests for public drunkenness, and
3) Dr. Walsh found that “free A.A.” made later hospitalization more expensive, and
4) Doctors Orford and Edwards found that having a doctor talk to the patient for just one hour was just as effective as a whole year of A.A.-based treatment.
5) Dr. George E. Vaillant, the A.A. Trustee, found that A.A. treatment was completely ineffective, and raised the death rate in alcoholics. No other way of treating alcoholics produced such a high death rate as did Alcoholics Anonymous.
http://www.orange-papers.org/orange-letters85.html

1) http://www.orange-papers.org/orange-effectiveness.html#Brandsma
2) http://www.orange-papers.org/orange-effectiveness.html#Ditman
3) http://www.orange-papers.org/orange-effectiveness.html#Walsh
4) http://www.orange-papers.org/orange-effectiveness.html#Orford
5) http://www.orange-papers.org/orange-effectiveness.html#Vaillant

Add your own answer in the comments!